カルスポリン
カルスポリン

Optimizing the gut microbiota of poultry and livestock

Poultry Swine Cattle

"Calsporin": Proven safety for more than 30 years of usage.

  • “Calsporin” is a live microbial product for poultry, swine and cattle containing Bacillus subtilis C-3102 as its active ingredient.
  • In Japan, it was approved as feed additives (Classification = Probiotics) effective for improving productivity, including improving growth and feed conversion rates, for swine and cattle in 1995 and for poultry in 1996.
  • U.S. : Listed in the official publication issued by AAFCO as a type of microorganism reviewed by the FDA as “generally recognized as safe (GRAS)” for use as feed from a safety perspective. Available as “Direct-Fed Microorganisms (DFMs)” found to present no safety concern.
  • Europe : Authorized as a zootechnical feed additive (functional group: gut flora stabilizer) by the European Food Safety Authority and meets all safety standards in the EU guidelines.
  • “Calsporin” Organic is listed by OMRI (the US Organic Materials Review Institute) for organic production.

Quality and safety management system based on EU Requirement

Certified under the European Quality and Feed Safety Management System for Specialty Feed Ingredients (FAMI-QS)

FAMI-QS

FAMI-QS USA

Application & Features

  • Bacillus subtilis, the active ingredient in “Calsporin” is an aerobic bacterium and is not an intestinal bacterium, so it does not colonize the intestines or propagate in the manner seen in indigenous intestinal bacteria. When “Calsporin” is supplied at a single dose, they pass through the alimentary track with feces in a few hours to several days. For supporting poultry and livestock that are constantly exposed to stress, daily supplementation of “Calsporin” is recommended.


  • “Calsporin” is a highly stable product that is highly heat resistant and accommodates pellet processing because it contains Bacillus subtilis in its spore form.

Product form

Bacillus subtilis C-3102


About “Calsporin”
About “Calsporin” in Spanish
About “Calsporin” in Portuguese

※Expressions or figures shown in above videos have been checked to comply with Japanese regulations.

History of “Calsporin”: Approvals, Permissions, and Registrations

1995 Approved as feed additives (probiotics) for swine and cattle by the Ministry of Agriculture, Forestry and Fisheries (Japan)
1996 Approved as feed additives (probiotics) for chickens by the Ministry of Agriculture, Forestry and Fisheries (Japan)
2001 Obtained sales-permit in Thailand
2004 Obtained sales-permit in China
2006 Authorized as zootechnical additive (gut flora stabilizer) for poultry (EU)
2010 Authorized as zootechnical additive (gut flora stabilizer) for piglets (EU)
2016 Authorized as zootechnical additive (gut flora stabilizer) for avian species for laying and ornamental fish (EU)
2017 Authorized as zootechnical additive (gut flora stabilizer) for sows, suckling piglets and dogs (EU)
2018 Authorized as zootechnical additive (gut flora stabilizer) for fattening pigs (EU)
2019 Approved as feed additives (Russia)