"Calsporin": Proven safety for more than 30 years of usage.
“Calsporin” is a live microbial product for poultry, swine and cattle containing Bacillus
subtilis C-3102 as its active ingredient.
In Japan, it was approved as feed additives (Classification = Probiotics) effective for
improving productivity, including improving growth and feed conversion rates, for swine and
cattle in 1995 and for poultry in 1996.
U.S. : Listed in the official publication issued by AAFCO as a type of microorganism reviewed by
FDA as “generally recognized as safe (GRAS)” for use as feed from a safety perspective.
“Direct-Fed Microorganisms (DFMs)” found to present no safety concern.
Europe : Authorized as a zootechnical feed additive (functional group: gut flora stabilizer) by
the European Food Safety Authority and meets all safety standards in the EU guidelines.
- “Calsporin” Organic is listed by OMRI (the US Organic Materials
Review Institute) for organic production.
Quality and safety management system based on EU Requirement
Certified under the European Quality and Feed Safety Management System for Specialty Feed Ingredients
Application & Features
Bacillus subtilis, the active ingredient in “Calsporin” is an aerobic bacterium and is
not an intestinal bacterium, so it does not colonize the intestines or propagate in the manner
seen in indigenous intestinal bacteria. When “Calsporin” is supplied at a single dose, they pass
through the alimentary track with feces in a few hours to several days. For supporting poultry
and livestock that are constantly exposed to stress, daily supplementation of “Calsporin” is
“Calsporin” is a highly stable product that is highly heat resistant and accommodates pellet
processing because it contains Bacillus subtilis in its spore form.
Bacillus subtilis C-3102
About “Calsporin” in Spanish
About “Calsporin” in Portuguese
※Expressions or figures shown in above videos have been checked to comply
with Japanese regulations.
History of “Calsporin”: Approvals, Permissions, and Registrations
||Approved as feed additives (probiotics) for swine and cattle by the Ministry of
Agriculture, Forestry and Fisheries (Japan)
||Approved as feed additives (probiotics) for chickens by the Ministry of Agriculture,
Forestry and Fisheries (Japan)
||Obtained sales-permit in Thailand
||Obtained sales-permit in China
||Authorized as zootechnical additive (gut flora stabilizer) for poultry (EU)
||Authorized as zootechnical additive (gut flora stabilizer) for piglets (EU)
||Authorized as zootechnical additive (gut flora stabilizer) for avian species for laying
and ornamental fish (EU)
||Authorized as zootechnical additive (gut flora stabilizer) for sows, suckling piglets
and dogs (EU)
||Authorized as zootechnical additive (gut flora stabilizer) for fattening pigs (EU)
||Approved as feed additives (Russia)